EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

ANAESTHETIC MANAGEMENT OF A PATIENT WITH HUNTINGTON’S CHOREA - A CASE REPORT

Dr. Akansha Singh, Dr. Shweta Mahajan*, Dr. Cliffin Mathai Kattoor, Dr. Abhinav Kumar and
Dr. Jyotsna Guleria

ABSTRACT

Huntington's disease is a rare dominantly inherited progressive autosomal disease affecting the basal ganglia. The disease manifests later in life as progressive mental deterioration causing personality change and involuntary choreiform movements. The most ominous motor symptom, dysphagia, hinders nutritional intake and places the patient at an increased risk of aspiration. The real challenge for an anaesthetist in the management of a patient with Huntington’s chorea lies in treating the frail elderly uncooperative patient, treating the patients suffering from malnutrition and dealing with increased risk of aspiration and exaggerated response to Succinylcholine and Thiopentone in these patients. We report the anesthetic management of a 62-year-old female patient with Huntington's chorea admitted for an elective orthopedic procedure.

Keywords: Huntington's disease; Basal ganglia; Involuntary choreiform movements; Autosomal; Personality change; GABA.

[Full Text Article] [Download Certificate]