EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

ANTIMICROBIAL SUSCEPTIBILITY OF SALMONELLA SEROTYPES ISOLATED FROM HUMAN IN WEST-AFRICA (BURKINA FASO, MALI AND NIGER).

Hadiza Bawa Ibrahim*, René Dembélé, Gertrude Bsadjo Tchamba, Isidore Juste O. Bonkoungou, Flabou Bougoudogo, Alfred S. Traoré and Nicolas Barro

ABSTRACT

Acute diarrhea in developing countries can be caused by a broad spectrum of enteric pathogens including Salmonella enterica. The aim of this study was to determine the profile diversity among Salmonella isolates and the distribution of resistant phenotypes in West-Africa (Burkina Faso, Mali and Niger). Strains were isolated by the conventional method from diarrheal stools patients. Strains were confirmed using Analytical Profile Index 20 Enteric and serotyped using specific antisera. The isolates were tested for antibacterial resistance using the agar diffusion method with fourteen commonly used antibiotics. The double-disk synergy test for confirmation of extended spectrum beta-lactamase activity was carried out by using amoxicillin–clavulanate against cefotaxime, ceftriaxone or cefepime. A total of 131 Salmonella strains were collected from the three countries with different proportions: 37% (48/131) to Burkina Faso, 48 % (63/131) to Mali and 15% (20/131) to Niger. The antibiotic susceptibility to different serotypes tested recorded the high resistance of Salmonella Paratyphi B to chloramphenicol. Salmonella Enteritidis showed only resistance to tetracycline. Resistance was observed to imipenem with Salmonella Paratyphi B and Salmonella Paratyphi C. Salmonella serotypes resistance study showed that 96% (126/131) were resistant to one or several antibiotics and 20% (26/131) were multiresistant. Six percent 6% (8/131) of Salmonella enterica isolates were producers of extended spectrum beta-lactamase. This study highlight emergence of multiresistant Salmonella to antibiotics in West Africa. Salmonella surveillance must be making in place in these countries and other African countries to improve epidemiological analysis of strains.

Keywords: Salmonella serotypes, antimicrobial susceptibility, Burkina Faso, Mali, Niger.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )