EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

ELCTROCARDIOGRAPHIC AND ECHOCARDIOGRAPHIC CHANGES IN SUBCLINICAL PRIMARY HYPOTHYROIDISM

Dr. Roha Shad and *Dr. Shubham Sharma

ABSTRACT

Introduction: The cardiovascular system is one of the most important targets of thyroid hormones and is very sensitive to a minimal decrease of circulating thyroid hormones. This study was done to assess the cardiovascular parameters in newly diagnosed subclinical hypothyroid patients by using Electrocardiogram and Echocardiography. Material and Methods: The present study included 25 patients. Results: ECG changes like Sinus Bradycardia were seen in 16% of patients, AV block was seen in 8%, low voltage complex was seen in 24%, generalized and non-specific t wave inversion was seen in 4%.The left ventricular end-systolic diameter and left ventricular end-diastolic diameter did not differ from the normal values. The mean left ventricular posterior wall thickness was 9.12±0.85 and Mean interventricular septum thickness was 9.152±0.749 in the study group, which were increased. A significant association was found between the occurrence of increased LVPW thickness and the severity of disease. A similar relationship was also demonstrated for abnormal IVSW thickness. IRT was significantly prolonged in subclinical group and E/A ratio was reduced. These two parameters directly represent the impaired diastolic dysfunction. Mild pericardial effusion was found in 3 individuals of subclinical group. Conclusion: This study suggests that it is very important to evaluate patients of subclinical hypothyroidism for cardiovascular changes so that prior interventions could be performed to improve the clinical outcomes.

Keywords: Hypothyroidism, Echo, IRT.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database