NAILING THE NAIL TROUBLE BY TRANSUNGAL DRUG DELIVERY
Pradeep S. Patil*, Sangita V. Badgujar and Ashwin A. Torne
Clean and beautiful nails are unique assets of your personality. Topical nail preparations like lacquers, enamel, and varnish are an integral part of today‟s beauty treatments. It protects the nail plate, but more importantly it enhances their beauty, imparting color and luster. Humans and animals alike are commonly plagued by the infiltration of
microorganisms beneath the nail, these results in various nail disorders. The aim of this review is to explore and overcome the difficulties in penetration of drug across nail plate & enhancement of bioavailability of antifungal drug. The current research data suggests that a key to successful treatment of nail diseases is a transungal drug delivery system. For nailing the nail troubles various techniques are used which range from use of chemical penetrators to physical and mechanical means of drug delivery. This review also covers the current clinical trial overview across the globe in brief.
Keywords: Transungal, Onychomycosis, Nail psoriasis, Clinical Trials.
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