DRUG DISCOVERY & DEVELOPMENT: A REVIEW ARTICLE ABOUT GOALS, PHASES, TOOLS OF DRUG DEVELOPMENT AND CHEMICAL COMPOUND LIBRARY

Priya Pandey1, Dhiraj Kumar*2, Mohd. Naeem Salam3, Tannu Yadav4, Preeti Yadav5 and Preeti Rani6

ABSTRACT

This article provides brief information about the discovery and development. Drug discovery is a long process that may take many years (12-15 years) for designing and developing a few therapeutically effective drugs. It is a very complex, time time-consuming cost-effective process. There are approximately 10,000 compounds are taken for testing in labs 100 compounds are looking for hit molecules from them approx. 10 compounds are found to be lead compounds and only 1 compound is approved as a therapeutically effective drug approved for marketing and use. Drug development and discovery include a number of steps and phases in their process. Nowadays there are various latest tools and technologies used in the development and discovery process. These tools and technologies are easy, less time-consuming accelerated (ADME – Tox) assessments. They can reduce the number of chemical compounds to be evaluated. This review article provides a brief overview and knowledge about the process, phases, tools, and techniques of Drug Discovery and Development process.

Keywords: Drug discovery, Drug development, phases, goals, tools, chemical compound library, FDA approval.