CLINICAL, LABORATORY, AND IMAGING FEATURES OF COVID-19; A SYSTEMATIC REVIEW AND META-ANALYSIS

Sambhana Sai Yagneswari*, Syed Moushmi and Teki Venkata Srujana

ABSTRACT

Coronavirus, Covid-19 (SARS-CoV-2), is a chronic respiratory syndrome. The first case of the corona was found in Wuhan city of China. This pathogen affects humans severely and leads to life-threatening conditions which require specialized treatments, and in some severe cases, patients will be treated in intensive care units. In this study total of 300 articles were retrieved, including 40 case reports. For complete text assessment, 40 articles were selected based on the screening using title and abstract; due to lack of molecular Diagnosis, five themes were excluded from this, and 35 were included for the study. A further seven were used for quantitative meta-analysis and 28 case reports for descriptive analysis. It was found that Patients with several comorbid conditions or chronic disease morbidity will be the vital parameter to consider during COVID-19 infections. Most patient with breathing difficulty in case of this infection needs supportive care in intensive care units. Unfortunately, the availability of the ICU is limited in most developing countries. Like other viral infections, common symptoms of the COVID-19 are fever, cough, and dyspnea, and the disease has fast progression if left untreated. The clinical investigation was leucopenia, increased C reactive protein, leading to ADR progression.

Keywords: COVID-19, ICU, Coronavirus, Systemic review, Meta-analysis.