EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

EVALUATION OF ANTI – CANCER ACTIVITY OF METHANOLIC AND AQUEOUS EXTRACTS OF ABUTILON INDICUM LINN BY IN- VITRO METHOD

Tarique Hussain, *Ravi Kumar Vishwakarma, Asha Rani, Randhir Kumar Gupta and Deepak Kumar

ABSTRACT

Abutilon indicum belonging to family Malvaceae is distributed throughout number of tropical and subtropical areas and subtropical zones and has been used for various disorders in traditional and folk medicine. Medicinal herbs play an important role in primary health care system among rural population since synthetic anti-cancer remedies are beyond the reach of common man because of the cost factor. The herbal medicines have a vital role in the prevention and treatment of cancer which execute their therapeutic effect by inhibiting cancer activating enzymes and hormones, stimulating DNA repair mechanism. Methodology: Extract were tested for the presence of active principle agents such as Triterpenoids,Steroids,Glycosides,Saponins, Alkaloid, Flavonoids, Tannins, Proteins, Free Amino Acid, Carbohydrate and lignin. Results: The result of the study shows Methanolic and Aqueous Extract possessed an Anti-neoplastic property comparing these two extracts Methanolic extract is more potent than Aqueous extract.) Were evaluated against six different cell lines (Lung A549, NCI-H23, Colon -205, SW- 620, Liver- HEP- 2, Ovary –OVCAR—5, Breast-mcf- 7, Prostate – DU – 145). Comparing Methanolic and Aqueous Methanolic extract exhibited 95% of the Anti-neoplastic potential against the Human Cancer cell origins.

Keywords: Abutilon indicum, Anti-Cancer, Flavonoid‘s, Malvaceae.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database