EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

THE EFFECT OF BLOOD CLOTTING EFFECTS IN SNAIL, ACUSTA DESPECTA SIEBOLDIANA

Man Kyu Huh* and Yong Lim

ABSTRACT

Snail, Acusta despecta sieboldiana (Pfeiffer) is a genus of family Bradybaenidae and a terrestrial pulmonate gastropod mollusk. We investigated the blood clotting activity from Acusta despecta sieboldiana. Adenosine diphosphate (ADP) is a platelet agonist that causes platelet shape change and aggregation. When the water extract was added with 40 mg/ml of extract, it had a blood clotting or cohesive effect of about 14%. Prothrombin time (PT) and activated partial thromboplastin time (aPTT) are measured the time it takes for blood to clot. The mean of PT in the water, ethanol, and methanol extracts were 11.2 s, 11.6 s, and 11.7 s, respectively. The time was 32.1 seconds on the 5 mg/ml water extract. Ethanol extract was 33.9 seconds on same concentration and methanol extract was 33.9 seconds. The international sensitivity index (ISI) was 1.3 for three extracts of snail mucus. International normalized ratio (INR) decreased in the high concentration exposure of snail mucus. In this study, snail mucus extract can partially help blood clotting when the wound is low in the agricultural field, but it did not have a significant effect. As a result of this study, it is expected that snail mucus extract can be used for blood coagulation as a hemostatic agent.

Keywords: Snail, Acusta despecta sieboldiana, adenosine diphosphate (ADP), Activated Partial Thromboplastin Time (aPTT), Prothrombin Time (PT).


[Full Text Article]

INDEXING

NEWS & UPDATION

  • EJPMR: JANUARY ISSUE PUBLISHED

    JANUARY issue has been successfully launched on 1 JANUARY 2023.

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 January 2023 Issue has been Published, Kindly check it on https://www.ejpmr.com/issue

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database