EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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 ICV - 79.57

Abstract

STUDY OF PATTERNS OF ANTIBIOTIC SENSITIVITY OF URINARY TRACT INFECTIONS

Dr. Suharshi Gupta*

ABSTRACT

Background: Urinary tract infections (UTIs) are one of the most common bacterial infections in human. Catheter-associated UTIs are one of the most dangerous health risks contributing 34% of all health care associated infections. Extensive and inappropriate use of antimicrobial agents has resulted in the development of antibiotic resistance which has become a major problem worldwide. The objective of the present study was to highlight the bacterial etiology of UTIs and determination of resistance pattern of E. coli isolates. Method: A cross-sectional prospective study was carried out in the Department of Microbiology, Govt. Medical College, Jammu (J&K), India, over a period of 6 months, i.e. from April 2021 to September 2021, among the reported OPD and indoor patients of GMC Jammu, in the age group of 18 to 90 years. Results: Of the 894 urine samples processed 455 (50.89%) gave significant growth of pathogens. The patients were between 18 and 90 years of age. The prevalence of UTI was high among females (63.08%) than males (36.92%). Females of the reproductive age group (18-49 years) constituted 53.40% of the total patients with UTI. However, elderly (50-90 years) males had a higher incidence of UTI (10.11%) compared to the elderly females (9.67%). Rate of E. coli (264, 58.02%) isolation was highest followed by Staphylococcus aureus (51, 11.2%). E. coli was found sensitive to meropenem, imipenem and amikacin (almost 100%), with good susceptibility to Ciprofloxacin (88%). Overall, 97% of the isolates were sensitive to Imipenem, 98.1% to Meropenem, while 90.3% are sensitive to Amikacin, 81.1% to Nitrofurantoin and 70.4% to Gentamicin. Conclusion: Culture positive rate for uropathogens was high, majority coming from adult female patients. E.coli was the most common etiological agent but still susceptible to nitrofurantoin. Nitrofurantin, Imipenem and Amikacin are good choice to tackle the upcoming problems of ESBL producing E.coli.

Keywords: Urinary Tract infection, Escherichia Coli, Prevalence, Antibiotic Sensitivity.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia