EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

ASSESSING THE EFFICACY AND SAFETY OF A TREATMENT REGIMEN COMPRISING ASPIRIN, PROMETHAZINE, AND MULTIVITAMIN COMBINATION FOR MILD TO MODERATE SYMPTOMATIC SUBJECTS OF COVID 19: A RANDOMIZED CONTROLLED TRIAL

Dr. Vidyadhar G. Vaidya*, Mr. Rohit Shelatkar, Dr. Atul Vadgaonkar, Dr. G. Sunil Kumar, Dr. Srilata Purunaik, Dr. Gayatri Ganu and Dr. Shashank Joshi

ABSTRACT

Introduction: The COVID-19 pandemic with the emergence of numerous variants is concomitant with high morbidity and mortality. To assess the efficacy and safety of treatment regimen comprising aspirin, promethazine, and multivitamin combination for mild to moderate symptomatic subjects of COVID-19. Trial design: A randomized controlled clinical trial was conducted using an interventional drug regimen, APMV2020, comprising two tablets A: a combination of aspirin and promethazine, B: multivitamins and trace elements, on 60 COVID-19 positive subjects. Methodology: The subjects were randomized to receive either the control intervention (clinical management protocol for COVID-19 advocated by the Indian Council of Medical Research (ICMR), Ministry of Health and Family Welfare, Government of India) or the test intervention (Treatment with APMV2020 tablets along with the standard control treatment. The assessment days were baseline, day 5 and 10. Results: APMV2020 significantly (<0.05) improved symptoms of COVID-19 like cough, breathlessness and fatigue, myalgia, headache, diarrhea, anosmia as compared to the control group. APMV2020 treatment also reduced inflammatory markers like LDH, ferritin and CRP. Conclusion: The APMV2020 treatment for COVID-19 provides better and faster clinical recovery of subjects suffering from COVID-19 symptoms, besides averting the possible disease progression. This may be the promising approach to recover patients of COVID-19.

Keywords: Aspirin, Vitamin C, promethazine, zinc, selenium, vitamin D, COVID-19.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • EJPMR: JANUARY ISSUE PUBLISHED

    JANUARY issue has been successfully launched on 1 JANUARY 2023.

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 January 2023 Issue has been Published, Kindly check it on https://www.ejpmr.com/issue

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database