FORMULATION AND EVALUATION OF HERBAL AQUEOUS GEL FOR MOUITH ULCER

*Ajay S. Dongarwar, Dinesh P. Borkar, Dhanshree R. Burade, Devendra K. Bisen, Mohit V. Bhalotia and Harshad S. Bhatheja

ABSTRACT

Background: Mouth ulcers often cause pain and irritation of the sores by salty, spicy and sour food items and may cause discomfort while healing occurs due to the use of chemical formulations. This project focuses on the preparation of a herbal mouth ulcer healing gel because of better cultural acceptability, better compatibility with human body and lesser side effects. The gel was prepared by using alcoholic extract of Psidium guajava, and aqueous extract of liquorice. Objective: The Present investigation was performed to formulate and evaluate the antiulcer activity of herbal gel containing guava leaves and liquorice root extract. Method: The Guava leaves collected and drying it by using hot air oven. Extraction was done by using soxhelet method by using ethanol as solvent. Liquorice root is collected dried in sunlight. Extraction was done by using soxhelet method by using ethanol as solvent. Evaluation of Antiulcer of both extract was carried out by 1. Determination of clarity and color 2. Determination of Odor 3. Determination of Viscosity 4. Determination of the Ph 5. Determination of Spread ability Result: Evaluation of antiulcer activity of the gel containing extract of guava leaves and liquorice root was evaluated by determining. Conclusion: We conclude that formation of liquorice root and guava leaves extract containing gel is effective in mouth ulcer.

Keywords: Liquorice root, Guava Leaves, Piperment oil, Glycerine, Soxhelet Appratus.