EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

COMPARATIVE EVALUATION OF CHLORHEXIDINE GLUCONATE AND POVIDONE IODINE MOUTHWASHES ON PLAQUE ACCUMULATION AND GINGIVAL INFLAMMATION AMONG ADULT POPULATION OF ALIGARH- A RANDOMIZED CONTROLLED TRIAL

Neha Agrawal*, Anshul Aggarwal, N. D. Gupta, R. K. Tewari, Juhi Gupta and Syed Amaan Ali

ABSTRACT

Context: Dental plaque has been connected to the most frequent infectious oral diseases in humans: caries and periodontal disease. The removal of bacterial biofilm is an important part of preventing and treating oral diseases. Adjunctive antimicrobials have been shown to improve clinical indicators by interfering with metabolic activities. Aims: To compare the effect of Chlorhexidine gluconate and Povidone Iodine mouthwashes on plaque accumulation and gingival inflammation among the adult population of Aligarh. Settings and Design: A parallel-group double-blind Randomized controlled clinical trial was carried out on systemically healthy 100, 20-50yr old adult patients having gingival inflammation and coming to the OPD of Dental College, Aligarh. Methods and Material: Patients with plaque induced gingivitis, as defined by the American Academy of Periodontology (Mariotti 1999), involving five adjacent teeth (FDI teeth 31–35) were included. At the baseline, scaling was performed, and the patients were randomly allocated by the toss of a coin either to the Chlorhexidine gluconate or povidone-iodine mouthwash group. After 4 weeks of use of mouthwash, the gingival index and plaque index were measured using a Williams periodontal probe. Statistical analysis used: SPSS 16 software was used for analysis. An Independent sample t-test and Chi-square test were utilized. Results: None of the parameters were statistically significant, however, the mean Plaque Index (PI) and Gingival Index (GI) values in the Chlorhexidine gluconate group were greater than those in the Povidone Iodine group. Conclusions: Povidone Iodine had a better overall effect on plaque and gingival inflammation than Chlorhexidine digluconate.

Keywords: Chlorhexidine digluconate, Povidone-iodine Plaque, Gingivitis.

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