ETHOSOMAL GEL; AS NOVEL DRUG CARRIER FOR TRANSDERMAL DRUG DELIVERY SYSTEM
*Swarupa Thavare, Tejeswini Deshmukh and Rutuja Rayjade
Ethosomal systems are lipid vesicular carriers that have a high ethanol content. These nanocarriers have been designed to circumvent the limits of traditional oral treatment. Which transport drugs deep into the layers of the skin. The production of these nanocarriers involves a variety of approaches For its structure and content, this system provides increased skin permeability and efficient bioavailability. Ethosomal dispersions are included in gels for patient compliance and stability. This publication gives a composition, detailed type of ethosomes, mechanism of drug penetration, formulation methods, advantages and disadvantages, evaluation, and examples for drugs used in ethosomal systems. Enhanced delivery of bioactive molecules through the skin and cellular membranes using an ethosomal carrier opens numerous challenges and opportunities for the research and future development of novel improved therapies.
Keywords: Transdermal drug delivery, Nanocarrier; Ethosomes.
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