EFFECTIVENESS OF PLATELET RICH PLASMA (PRP) IN PAIN MANAGEMENT OF OSTEOARTHRITIS (OA) KNEE

Dr. Asiful Haque*, Dr. Md. Amanath Ullah, Dr. Fatama Sharmin, Dr. Ziaur Rahman Chowdhury, Dr. S. M. Mazharul Islam, Dr. H. N. Masuk Rahman

ABSTRACT

Introduction: Osteoarthritis (OA) is an ongoing joint illness that typically happens in more established individuals and prompts torment and incapacities. OA treatment goes from drug treatment to medical procedure. Medication and restoration treatment are liked over a medical procedure, and, particularly, there is an inclination toward intensifies causing regenerative changes in the knee joint. In the current investigation, the impacts of platelet-rich plasma (PRP) infusion and prolotherapy (PRL) were inspected fair and square of torment and capacity of the knee joint in patients with OA. Methods: After satisfying the incorporation rules and marking the educated assent structure, 84 patients with knee OA were booked for intra-articular infusion in the present randomized, twofold visually impaired, clinical preliminary. Following admission to the working torment room, the state of the patient's knee was assessed first through the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and, then, at that point, ultrasound-directed knee infusion was finished. Appropriately, patients in the PRP treatment bunch got 7 mL PRP arrangement and those in the PRL bunch got 7 mL 25% dextrose. Utilizing the WOMAC, levels of agony and knee work were assessed and recorded for every persistent promptly before the primary infusion just as at multi month (quickly preceding the subsequent infusion), 2 months (a month after the subsequent infusion), and a half year after the fact. Information gathered were investigated utilizing the SPSS v.20. Results: During the first and second months, a quick reduction in the in general WOMAC score was seen in the two gatherings. The generally speaking WOMAC score expanded at the 6th month, however was lower than the by and large WOMAC score in the main month. Measurable investigation demonstrated that the by and large WOMAC score fundamentally diminished in the two gatherings of patients more than a half year. Conclusion: Results of the current examination recommended a critical reduction in the by and large WOMAC score of patients who go through either PRP treatment or PRL. This positive change in the generally speaking WOMAC score prompted an improvement in the personal satisfaction of patients with knee OA soon after the principal infusion. PRP infusion is more successful than PRL in the treatment of knee OA.

Keywords: knee osteoarthritis, platelet-rich plasma, prolotherapy, ultrasound.