EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

THE EFFECTS OF URINARY TRACT INFECTION ON ANTIOXIDANT STATUS AMONG PREGANANT WOMEN

Varsha N. Bhat* and Veena Shetty

ABSTRACT

Background:- The aim of the study was to investigate the etiology of UTI and its antibiotic profile in pregnant women; and to assess the excretion of urinary malondialdehyde (MDA) and antioxidants like superoxide dismutase(SOD) levels in pregnant women with UTI and to compare them with healthy pregnant women without UTI and also to investigate if antioxidant enzymes and MDA differed in each trimester. Methods:- This is a cross sectional study carried out between November 2015 to April 2016 at K.S.Hegde Charitable Hospital, Deralakatte .The study included 100 pregnant women reporting to OBG &Gynecology OPD with complaints of UTI as well as healthy pregnant women without UTI symptoms. Biochemical analysis and microbiological culture of urine was done. Results:- Out of 100 samples 86 samples had no growth and 14 samples were positive for urinary pathogen. The prevalence of UTI infection in relation to age showed- individuals of age group 26-30 years had highest incidence of infection. Among the significant urinary isolate E.coli had highest prevalence. In the study there was significant variation between MDA,SOD values between pregnant women with UTI and healthy pregnant women. Trimester wise there was significant variation in MDA between 1st and 3rd trimester and SOD levels between 2nd and 3rd trimester which suggests that gestational period plays a major role in aggravation of UTI among pregnant women. Conclusion:- Pregnancy causes oxidative stress from first to third trimester and UTI may aggravate the oxidative stress during pregnancy. Screening with urine culture during pregnancy and treatment of asymptomatic bacteruria may provide modest reduction in pyelonephritis among women and may reduce number of preterm and low-birth weight infant. Increasing antibiotic resistance trends in UTI patients indicates that it is imperative to rationalize the use of antimicrobials to limit antibiotic resistance.

Keywords: Asymptomatic bacteruria, Urinary tract infection, Pregnant women.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database