EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

AN INVESTIGATION OF OSTEOARTHRITIS MANAGEMENT AT THE UNIVERSITY OF BENIN TEACHING HOSPITAL, BENIN CITY, NIGERIA

Joshua Ogiangbe Idiake*, Anthony Waka Udezi and Stella Folajole Usifoh

ABSTRACT

Introduction: Osteoarthritis (OA) is a degenerative disease that affects the joints of the body. There are different measures through which OA can be managed one of which is pharmacotherapy. Early detection and management is very crucial to the prognosis of the disease. Different patient factors especially co-morbid conditions influence the selection of these agents acclaimed for its management. Methodology: This retrospective study was conducted at the University of Benin Teaching Hospital. Information pertaining to OA management was obtained from the case notes at the records Department by the use of a data collection sheet. Data was analysed using SPSS version 24.0 and expressed in frequencies and percentages. With the use of graph-pad instat inferential statistics was done and a P-Value ≤0.05 was interpreted to be statistically significant. Results: Diclofenac (64.9%) was the most prescribed medication followed by paracetamol (22.1%), pregabalin (21.1%) and celecoxib (19.3%). Some patients with co-morbid hypertension (89.50%) were treated with NSAIDs while 87.18% of patients with co-morbid ulcer disease were treated with non-selective NSAIDs co-administered with gastro-protective agents. Omeprazole (81.62%) was the most commonly used gastro-protective agent. Patients’ co-morbid conditions were the only socio-demographic factor that influenced the choice of medication for the treatment of osteoarthritis. (P = O.O311). Conclusion: Diclofenac was the most commonly used medication in the treatment of OA and co-morbid condition was considered by physicians when recommending medications for OA treatment.

Keywords: Osteoarthritis, Treatment, Hospital, Side-effects, NSAIDs.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database