EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

EVALUATION OF INVITRO ANTI OXIDANT ACTIVITY ON THREE TRADITIONAL DRUGS

V. E. Ida Christi* and R. Senthamarai

ABSTRACT

Achyranthus aspera Linn, Moringa oleifera Lam and Scopharia dulcis Linn are used in the traditional system of medicine for the treatment of many diseases. Achyranthus aspera L (AA) belongs to the family Amaranthaceae, the whole plant and especially the roots, characterized by their uterine stimulant activity, are prescribed in the therapy of rheumatism, contusions, lumbago, osteodynia, dysuria, post-partum haematometra and dysmenorrhoea. There is no doubt that the pure Moringa oleifera L(MO) belongs to the family Moringaceae,this tree leaf is the source of incredible health benefits. It's the ultimate, natural, organic, energy and endurance health supplement. Scopharia dulcis L (SD) belongs to the family Scrophulariaceae, this plant has long held a place in herbal medicine in almost every tropical country where it grows, and it is much used by indigenous peoples. Then the antioxidant activity of the plants were evaluated by DPPH Method, Hydrogen peroxide scavenging activity, Nitric oxide scavenging activity, Antihemolytic activity, Reducing power determination methods. Three plants were estimated for their total flavonoid contents and total phenols contents. The flavonoids are a heterogeneous group of phenol compound present in the plant world. Many flavonoids, purified from medicinal plants and herbs used in the practice traditional medicine are endowed with biological effects. They include vasoprotective, anti-inflammatory, anti-allergic, anti-microbial, anti-hepatotoxic, anti-osteoporatic and anti-neoplastic. Structural aspects of antioxidant activity of flavonoid and the correlation between active oxygen scavenging and antioxidative effects of flavonoid have been studied. Flavonoids may directly scavenge some radical species by acting as chain breaking antioxidants or they may cycle other chain-breaking antioxidants such as tocopherols by donating a hydrogen atom to tocopherol radical. Transition mineral such as ferric and copper are important pro-oxidants and some flavonoids can chelate divalent metal ions, hence preventing free radical formation. And also vitamin C content present in these plants were estimated quantitatively, Vitamin C is also a good source for antioxidant activity. The plants shows significant effect on Antioxidant activity.

Keywords: Antioxidant, Antihaemolytic, Moringaceae, Scrophulariaceae.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database