EMULGEL – AN INNOVATIVE MODUS OPERANDI FOR FORMULATION OF HYDROPHOBIC DRUGS FOR THE TREATMENT OF DERMATOLOGICAL DISEASES

Lingam Harini*, Madappa Vaishnavi, Kothuri Jyothi, Kulthe Geetha and Hyma Ponnaganti

ABSTRACT

In this cutting-edge era, there have been a lot of advancements in the medical field to improve the health of individuals suffering from a wide range of diseases either caused by invading microorganisms or by abnormal functioning of body organs. One such example is the formulation of Emulgel, which is a type of topical gel, known to have greater absorptive and therapeutic properties when compared with liquid and solid dosage forms. The main principle applied in the preparation of Emulgel is the incorporation of transparent gel into the emulsion as a means to diminish the adverse effects of dermatological diseases. The amalgamation of an emulsion into gel gives it more stability and henceforth is gaining more popularity as a topical drug delivery system with the sustained-release property as well, in which the drug is released slowly with a specific time interval to give efficient and long-lasting action, along with it can also incorporate hydrophobic drugs, which is a major limitation observed in gel-based formulations. Eventually leads to an opportunity to cure dermatological diseases caused by viruses as well and not only constricted to bacteria or fungal infections.

Keywords: emulgels, hydrophobic drugs, skin, topical gel, drug delivery, in-vitro.