EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

HOME-BASED VERSUS CENTRE-BASED CARDIAC REHABILITATION OR USUAL CARE IN ELDERLY: A SYSTEMATIC REVIEW AND META-ANALYSIS

Zhiquan Wang* and Li Chee Cynthia Chin

ABSTRACT

Objectives: To evaluate the impact of home-based cardiac rehabilitation (CR) compared to centre-based CR or usual care (UC) on exercise capacity, health-related quality of life (HRQoL), cardiovascular events, and mortality in elderly patients. Methods: This study included randomised controlled trials comparing home-based CR against centre-based CR or UC in elderly patients with coronary heart disease or heart failure. PubMed, EMBASE, CENTRAL, WHO ICTRP and ClinicalTrials.gov were searched systematically on 27 August 2021. Cochrane RoB 2 tools was used for risk of bias assessment. For the meta-analysis, data were pooled using a random-effects model. Results: 19 studies were included, comprising 2,287 participants, contributed to 4 comparisons for home-based CR to centre-based CR, and 17 comparisons to UC. Compared to centre-based CR, the outcomes showed similar effects in terms of exercise capacity (SMD -0.02, 95% CI -0.33 to 0.29, P = 0.90) and HRQoL (SMD -0.25, 95% CI -0.67 to 0.17 P = 0.25). Compared to UC, home-based CR significantly improved exercise capacity (SMD 0.32, 95% CI 0.16 to 0.47, P < 0.0001) and HRQoL (SMD -0.26, 95% CI -0.40 to -0.11, P = 0.0005). For the secondary outcomes, home-based CR significantly improved the all-cause hospitalisation (RR 0.67, 95% CI 0.51 to 0.87, P = 0.003). Conclusion: Provision of home-based CR to elderly patients significantly improved exercise capacity and HRQoL compared to UC, and the effects of home-based CR was similar to centre-based CR. However, there is still limited evidence on the long-term impact of home-based CR in the elderly.

Keywords: Exercise training, coronary heart disease, heart failure, cardiovascular diseases, older adults.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database