FLOATING DRUG DELIVERY SYSTEM (FDDS): TYPES, ADVANTAGES, DISADVANTAGES & APPROACHES
Ram Nivas*, Suraj Mandal, Himani Gururani, Pragati Saxena, Sanjeev Kumar and Dr. Navneet Verma
In this review studying about the oral drug delivery system, where floating systems are low thickness frameworks that have adequate lightness to drift over the gastric substance and stay light in the stomach without influencing the gastric purging rate for a drawn-out timeframe. Floating drug delivery systems are planned to prolong the study of the dosage form in the g.i.t and help in enhancing the absorption. These types of systems are best suitable for drug having an improved solubility in acidic environment and also having specific site of absorption in upper part of the small intestine. Present review is to keep understanding or overcome the difficulties for the development of oral drug delivery system. FDDS are of particular interest of drugs that are locally active and have narrow absorption window in stomach or upper small intestine unstable in the intestinal and exhibit low solubility at high pH values FDDS in specific region of the GIT offers numerous advantages, especially the drugs having narrow absorption window in GIT, primary absorption in the stomach, Stability problems in the gut are caused by the stomach's poor solubility in alkaline pH. the reason that oral route achieved such popularity may be in part attributed to its ease of administration.
Keywords: Floating drug delivery systems (FDDS), Oral drug delivery systems (ODDS)
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