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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Dr. Md. Abdullah Al Mamun*, Dr. Mohammad Mirazul Hasan, Dr. Syed Mahbub Morshed, Dr. Ratan Das Gupta, Dr. Gobinda Chandra Roy and Dr. A. H. M. Nazmul Ahsan


Introduction: Glomerular disease is a leading cause of chronic kidney disease in developing countries as well as developed countries. In Bangladesh, prevalence of CKD and ESRD increasing mostly due to glomerulonephritis. Presentation of glomerular disease ranges from asymptomatic to life threatening acute complications. The prevalence of glomerular disease is different in various regions of the world. This study reflects pattern of glomerular disease and their clinicopathological and histological characteristics in Bangladeshi population. Objective: In this study our main goal is to Identify of Clinical and Histological pattern of glomerular disease can introduce earlier treatment and prevent chronic kidney disease and ESRD. Methods: This study has been conducted at department of nephrology, Shaheed Suhrawardy Medical College hospital from January 2017 to June 2018. 206 patients of glomerular disease included in the study with proteinuria >0.5gm/day or presence of RBC or RBC cast in urine and or renal impairment. Selected patients were evaluated with history, clinical examination and laboratory investigations. After taking consent renal biopsy was performed and histopathology (light microscopy and DIF) done by expert pathologist. Data were analyzed by using SPSS software. Result: Total 206 patients included in the study with mean age 34.5±14.13 years (13-70 years), female was predominant than male (61.5%). More than 50% of participant were less than 40 years of age. Most common presentation was edema (87.2%). Others were oliguria, hematuria, shortness of breath, hypertension, anemia, arthritis, skin rash, sore throat and features of renal failure. Histologically mesangial proliferative glomerulonephritis was more common variety among all (34.3%). Others were lupus nephritis (15%), membranoproliferative (MPGN) 12.1%, FSGS (11.6%), IgA nephropathy (5.8%), MCD (5.3%), membranous nephropathy (3.9%) and IgM nephropathy (2.9%). Histological diagnosis could not be performed remaining 8.7% of patient due inadequate sample or chronic sclerosing glomerulonephritis. Proteinuria varies in different type of glomerulonephritis with mean UTP 4.24±3.17 gm/day (0.5-19.7 gm/day). Renal impairment (serum creatinine >1.4 mg/dl) was found to be 50.49% (104) cases. More than 50% of patient with mesangial proliferative, membranoproliferative glomerulonephritis, FSGS, Membranous Nephropathy, Lupus Nephritis and IgA Nephropathy had renal impairment. Conclusion: Presentation of glomerulonephritis ranges from asymptomatic to chronic kidney disease. Early histological diagnosis is essential for management of glomerular disease to prevent CKD and other complications. The result of this study may helpful for treatment of glomerulonephritis and reduce glomerulonephritis related complications as well as prevent chronic kidney disease in our country.

Keywords: Glomerular, oliguria, hematuria, chronic kidney disease.

[Full Text Article]



  • New Issue Published

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    SEPTEMBER issue has been successfully launched on 1 SEPTEMBER 2023.

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    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database