EVALUATION OF ANTIDIABETIC ACTIVITY OF STEM BARK OF MURRAYA KOENIGII ON EXPERIMENTAL ANIMALS

Monika Upadhyay, Dr. Nasiruddin Ahmad Farooqui*, Dr. Shamim Ahmad and Jiyaul Hak

ABSTRACT

The current study is an effort to examine the effect of Murraya koenigii stem bark extract on streptozotocin induced diabetes in Wistar rats. Two groups of streptozotocin persuaded diabetic rats were orally treated through Murraya koenigii stem bark extract (200 and 400 mg/kg) respectively. The blood glucose level, body mass, Glycosylated hemoglobin, liver glycogen, lipid profile, Antioxidant status were measured at the finish of the study that is after 28 days of treatment. Murraya koenigii stem bark extract were originate to be significant (p < 0.001) in dropping the blood glucose level, glycosylated hemoglobin, triglyceride, cholesterol, blood urea, lipid profile, while both the treatments improved body weight, liver glycogen satisfied status once compared to the diabetic control. It have been concluded that Murraya koenigii stem bark extract, in adding to the antidiabetic activity in the streptozotocin induced diabetic model.

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