BIOLOGICAL IMPORTANCE OF THIAZOLIDINONES

Indu Singh*

ABSTRACT

Thiazolidinone belongs to heterocyclic compounds having sulfur & nitrogen atom in a five member nucleus. Thiazolidinone is saturated structure of thiazole included carbonyl group on the fourth position of carbon. Different type of substituent of heterocyclic ring incorporating in thiazolidinone nucleus produces wide range of biological activities. Researchers and scientists have developed various new compounds having thiazolidinone and screened them for various pharmacological activities with least side effects. These thiazolidinone derivatives shows its significance such as antimicrobial, anti-inflammatory, antibacterial, anticonvulsant, analgesic activities etc. From the literature survey it has been found that thiazolidinone nucleus is biological active and easy to synthesized. This review article aims emphasize diverse biological activities of thiazolidinone.

Keywords: Thiazolidinone, biological activities, antimicrobial activity, anti-inflammatory activity.