EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database ,

ISSN 2394-3211

Impact Factor: 6.222

ICV - 79.57

Abstract

FIRST ORDER DERIVATIVE METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF ATROPINE SULFATE AND DEXAMETHASONE

Vaghasiya Vivek and Dr. Kashyap Raval*

ABSTRACT

Analysis of pharmaceutical product is very important as it concerned with quality of life. The objective of present work is to develop and validate First order Derivative UV Spectrophotometry method for estimation of Atropine sulfate and Dexamethasone in its combined Liquid dosage form. Estimation of Atropine sulfate and Dexamethasone were carried out at λmax 239.60 nm and 246.68 nm for First Order Derivative Spectrophotometry Method, Using Methanol as a solvent. Linearity of Atropine sulfate and Dexamethasone were found to be 100-350 μg/ml and 10-35 μg/ml respectively. UV Spectophometric method was validated as per ICH guideline Q2 (R1), for its accuracy, Precision, LOD & LOQ and the results were found to be satisfactory. Developed and validated method was found to be simple, accurate, economical, robust and reproducible & method can be successfully applied for routine QC analysis.

Keywords: Atropine sulfate, Dexamethasone, First order derivative spectrophotometry, Methanol.

[Full Text Article]

SJIF Impact Factor: 6.222

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NEWS & UPDATION

New Issue Published
Its Our pleasure to inform you that, EJPMR 1 November 2023 Issue has been Published, Kindly check it on https://www.ejpmr.com/issue

EJPMR: NOVEMBER ISSUE PUBLISHED
November issue has been successfully launched on 1 November 2023

EJPMR New Impact Factor
Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from 5.804 to 6.222, due to high quality Publication at International Level