VASCULAR MANIFESTATOIN IN SLE
*Dr. Rajesh Kumar, Dr. Medha Kaith, Dr. Raman Deep, Dr. Ajay Alhuwalia and Dr. Vijay Thakur
• SLE is autoimmune disorder with multisystem involvement and vascular manifestation are well known entity in SLE, involving multiple factors.
• Thrombosis prevalence in SLE is >10% and PAH prevalence being 0.5-17%.
• The pathophysiology involves multiple mechanism from vasculitis and in-situ thrombosis. Incidence of vascular manifestation is high in 1st year of disease because of high level of disease activity.
• Thrombosis is 2nd most common cause of death in SLE, behind active SLE. Early diagnosis, risk factors (APLA etc.) detection and treatment with hydrochloroquine (unless contraindicated) is necessary.
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