CHANGES IN SERUM CALCIUM LEVEL IN TERM AND PRE-TERM NEONATES WITH NEONATAL JAUNDICE BEFORE AND AFTER GETTING PHOTOTHERAPY IN A DISTRICT HOSPITAL, BANGLADESH

Tamanna Yesmin* and Marlina Roy

ABSTRACT

Background: Hyperbilirubinemia commonly seen in both term and preterm neonates who have jaundices which can be fatal. Though phototherapy can be used as effective techniques to reduction of Hyperbilirubinemia condition, where hypocalcemia cases were observed. Objectives: In this study our main goal is to evaluate the outcome of phototherapy in changing serum calcium level in preterm and term babies with neonatal jaundices. Method: This study was carried out at Combined Military Hospital, Chittagongfrom January 2019 to January 2020 among 50 full-term and pre-term jaundiced neonates. Before starting the treatments, a detailed antenatal, perinatal history and examination of the neonates was done. Results: During the study, 44% cases belong to 6-10 days age group followed by 60% were male. Among cases 65% were full-term and 35% were pre-term neonates. While during evaluating on the basis of causes of jaundice majority were belonging to breastfeeding jaundices, 65% followed by 25% cases were breast milk, 15%were physiological jaundices, 3% were Rh /ABO incompatibility and 2% were septic conditions. Before phototherapy. the mean ± SD of total serum bilirubin was 20.75 ± 10 mg / dl and after phototherapy was 9.05± 0.7mg / dl. The total serum bilirubin decreased significantly after phototherapy with a p value of 0.001. Whereas, the mean ± SD of serum calcium before phototherapy was 8.11 ± 0.11 mg / dl. and after phototherapy it was 6.79± 0.50. Levels of serum calcium decreased significantly after phototherapy when compared to values before phototherapy with p value 0.013. As neonates are asymptomatic neonates with serum calcium levels were treated with 2 ml/kg/dose of 10% calcium gluconate I/V slowly. After getting treatment, majority cases reach satisfactory level, 90%. Conclusion:From our study, we can say that, after treatment as no mortality was seen and majority reported as satisfactory level so, phototherapy can be used as an effective technique for treating Hyperbilirubinemia in neonates’ jaundices.

Keywords: Hyperbilirubinemia, Neonates’ jaundices, Phototherapy.