EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

STUDY OF ANTHELMINTIC AND ANTIMICROBIAL ACTIVITY OF PEEL EXTRACT OF PUNICA GRANATUM LINN.

Deore Leena P*., Bachhav Devidas G., Nikam Vikas K., Heda Amol J.

ABSTRACT

Punica granatum linn. (pomegranate) has been used for centuries to confer health benefits in number of diseases . The aim of present study is to identify phytochemical constituents and evaluation of antimicrobial and anthelmintic activities of peel extract of pomegranate. Antimicrobial activity of plant is due to its secondary metabolites. The antimicrobial activity of peel extract in aqueous, ethanol and methanol on E.coli, S.aureus, and B.subtilis was studied at different concentrations (1, 5, 10 mg/ ml). E. coli shows significant zone of inhibition in ethanol extract and S.aureus in aqueous extract, while B. subtilis shows in methanolic extract.The various concentrations (20, 50, 100, and 150 mg/ml) of aqueous, methanol and ethanol extracts were tested in-vitro for anthelmintic potency. It was determined by time required for paralysis and time required for death of earth worms. The peel extract shows dose dependant activity .The short time for paralysis and death was observed for methanol extract at concentration 150 mg/ml. From above observations it was concluded that the methanolic extract shows maximum response in dose dependant manner for antimicrobial and anthelmintic activities.

Keywords: Punica granatum linn., Pomegranate, Anthelmintic, Antimicrobial.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia