EFFECT OF MESUA FERREA FLOWER AND CARICA PAPAYA SEED EXTRACTS ON BIOCHEMICAL CONSTITUENTS OF OVARY, LIVER AND KIDNEY IN FEMALE ALBINO RATS

Dr. N. Raja Naik* and Dr. H. Ramasubba Reddy

ABSTRACT

The effect of Mesua ferrea (M.ferrea) flower and Carica papaya (C.papaya) seed extracts on the levels of total carbohydrates, proteins and lipids in the ovary, liver and kidney of female albino rats was studied. In this study was used (48) good healthy adult female albino rats were divided into two experiments (Experimentation: 1 and Experimentation: 2), and each experimentation was divided into four groups (Group-I, group-II, group-III and group-IV), each group consist six animals. The 1st experimental groups (except group-I) were treated with M.ferrea flower extracts (100 mg/kg, 200 mg/kg, 300 mg/kg body weight) orally once daily. The 2nd experimental groups (except group-I) were treated with C.papaya seed extracts (100 mg/kg, 200 mg/kg, 300 mg/kg body weight) orally once daily. The experimental period was 21 days. The result showed that there was the total carbohydrate and cholesterol content were significantly increased and protein concentration was decreased in all groups of M.ferrea flowers extract treated rats when compared with the control. There was also increased in the physical activity of the test groups, while the control did not show any noticeable change. The serum levels of total cholesterol in treated groups were significantly higher than the control. From observation, on the test groups of 2nd experimentation, the levels of carbohydrate, cholesterol and proteins were higher in all treated groups. Thus the effect may be depending on the quantity of the seed incorporated into the feedstuffs. Generally, there were increased levels of cholesterol and protein due to the incorporation of M.ferrea flower and C.papaya seed extracts into the feed of the animals used in this study.

Keywords: Carbohydrate, Protein, Cholesterol, Mesua ferrea, Carica papaya.