HYPONATREMIA IN HYPOPITUTARISM DUE TO LYMPHOCYTIC HYPOPHYSITIS

*Dr. Nitesh Kanwar MD Medicine and Dr. Neha Patial MD Radiodiagnosis

ABSTRACT

Hyponatremia is a common electrolyte disorder especially in the elderly but also as a laboratory sign of hypopituitarism. Hypopituitarism is a relatively rare condition that is often misdiagnosed. Several case series of hyponatremia associated with hypopitutarism have been reported. Hypopituitarism is an under investigated endocrine disorder in the elderly, since its clinical features are unspecific and more often attributed to aging itself. The misdiagnosis of hypopituitarism is common due to its rarity and its nonspecific clinical manifestations. Our case report highlights the importance of critical evaluation regarding hypopituitarism as a cause of recurrent, hyponatremia, and headache in patients, as misdiagnosis might be fatal to the patient. Panhypopituitarism is a condition of inadequate or absent production of the anterior pituitary hormones. It is associated with increased morbidity and mortality. Clinical manifestations are influenced by the cause, severity, and rate of onset of pituitary hormone deficiency. We herein described a case of recurrent hyponatremia complicated by hypopituitarism that was possibly due to lymphocytic hypophysitis. The development of recurrent hyponatremia, electrolyte abnormalities, and gastrointestinal symptoms; however, should arouse suspicion of glucocorticoid insufficiency. Our case report highlights the importance of evaluating hypopituitarism as a cause of recurrent hyponatremia.

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