EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

REPOSITIONING OF DRUGS: AN APPROACH FOR NEW DRUG DISCOVERY

Gayatri Chhatre and Dr. Vithal M. Kulkarni*

ABSTRACT

Drug repositioning (DR) (also known as repurposing or reprofiling) is the new strategy of research of nonexistent therapeutic indications and implementations for the existing drugs. It is basically recycling of approved, failed or banned drugs for various complex and deadly diseases. Currently, on an average, the cost for conventional de novo discovery and development of a drug is enormous and requires a minimum of 10 years for the drug to reach the market. On the contrary, Drug Repositioning is known to be the fastest and cost effective method of drug discovery. Few sources estimate the average cost of repositioning is cut down to $300mn and takes about 6.5 years to launch in the market. Cancer has been a challenge and a battle to overcome. The International Agency for Research on Cancer (IARC) estimated the global cancer burden to be risen to 19.3 million. World is working for the development of new drugs along the timeline of cancer to put patient suffering at ease with less toxic and effective drugs. Repositioning is a proficient way to discover new drugs and is a suitable approach to find remedy for cancer. This paper reviews repositioning of known drugs that display significant anti-cancer activity.

Keywords: Drug repositioning, Anti-HIV, Proton pump inhibitors, Anti-fungal, Anti-diabetics, NSAIDs, Anti-cancer.


[Full Text Article]

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  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 January 2022 Issue has been Published, Kindly check it on https://www.ejpmr.com/issue

  • EJPMR: JANUARY ISSUE PUBLISHED

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    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )