EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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 ICV - 79.57

Abstract

A COHORT STUDY OF THYROID HORMONE IN PEDIATRICS: CORRELATION WITH OBESITY IN SAUDI ARABIA

Turki Melfi Alharbi*, Faisal Hadi Almilfy, Faisal Abdullah Al-Abduljabar, Wail Altreef, Amal Abdulrahman Alsowaidi, Mohammad Abdulrahman Althnayan, Mohammed Abdulaziz Alkhalifah, Arwa Abdulaziz Almajdui, Alanoud Saleh Albuloshi, Abrar Abdulaziz Al-Ajlani, Mohammed Faisal Alsamih, Faisal Mohammed Alshehri, Faisal Abdullah Alabduljabar, Abdullah Abdulaziz Aleid, Abdullah Kulip Alonzi and Amani Abdullah Alharbi

ABSTRACT

For children to grow or increase in height properly they need adequate levels of need growth hormone (GH) or somatotropin (Qiu H, 2017), and thyroid hormone also is essential for bones development in childhood and regulation in adulthood, and they both have many other effects, and growth hormone disorders can cause growth abnormalities weather it is excess production or decrees, the coloration between growth hormone and thyroid hormone is important because secretion and action of both hormones can be effected by each other (Cabello G, 1989), although thyroid stimulating hormone (TSH) is the main thyroid hormone regulator other factors can affect the thyroid hormone including growth hormone, also thyroid can affect growth hormone, increased levels growth hormone have been can lead to acromegaly, and patients of acromegaly can also develop goiter an from an enlarged thyroid gland (Cabello G, 1989), and patients who suffer from decreased levels of growth hormone and receive growth hormone replacement therapy can develop alterations in the hypothalamic-pituitary-thyroid axis, and can result in different changes wither it is a decrees in thyroxine (T4) levels or no changes, also triiodothyronine (T3) it can be in variable changes in can be increased or unchanged. (Glynn N, 2016). There is wide verity of possibilities that can be the cause of these and other possible changes, in this study we aim to understand growth hormone correlation with thyroid hormones in children who take growth hormone replacement therapy, and evaluate the entire hypothalamic–pituitary–thyroid axis, and the thyroid hormone function in this situation, and the potential effect of these interaction and the clinical results, and improve our understands of these situations to try and improve the treatment.

Keywords: .


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )