EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

STUDY OF OBSTETRIC OUTCOME AND OPTIMUM MAGNESIUM SULPHATE DOSING SCHEDULE IN ECLAMPSIA PATIENTS AT A TERTIARY CARE HOSPITAL

Fasiha Tasneem*, Bhawna Parane and Vinutha M. Sharma

ABSTRACT

Background: Eclampsia is a common medical emergency of pregnancy mainly seen in 5% to 10% of all pregnancies. The objective of the present study was to find out the obstetric outcome of eclampsia patients and to find out the dosing schedule of magnesium Sulphate in eclampsia patients. Methods: All the cases of impending eclampsia and eclampsia getting admitted in tertiary care hospital are analysed prospectively for obstetric outcome and optimum magnesium sulphate dosing schedule over a study period of 18 months. Results: In this study of 248 patients, 114 of imminent eclampsia and 134 are of eclampsia. Incidence was higher in primigravida in the age group of 21-25 years. 62.1% delivered vaginally, 31.9% by caesarean delivery and 6% by instrumental delivery. All imminent eclampsia patients received 14 gm MgSO4 and in none of them convulsions occurred. In eclampsia patients, according to standard Pritchards regime, majority (38.8%) patients received 44 gm of MgSO4. Conclusion: To reduce the incidence and complication of eclampsia, there is a dire need to improve antenatal care at community level. MgSO4 as a drug of choice has stood the test of time for control of eclampsia and prevention of further convulsions. Even though various drugs and methods are tried, the definitive management for treatment of eclampsia is after control of convulsions and hypertension, delivery at tertiary care hospital. Termination should be individualized.

Keywords: Eclampsia, Hypertension, Convulsions, Magnesium Sulphate.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )