UNEXPLAINED BLEEDING - MANIFESTATION OF GLANZMANN’S THROMBOSTHENIA
Dr. Priti Kamble*, Dr. Nivedita Patil , Dr. Yamini S., Dr Hashiq N. and Dr. Jaiprakash Jaiswa
Glanzmann’s thrombosthenia(GT) is a rare inherited platelet disorder characterized by deficiency of platelet fibrinogen receptor alpha IIb β3. Here we report two cases of GT from single family born to parents with 3 degree consanguineous marriage. Among the two cases, older sibling i.e 3.5years old female child presented with ecchymosis and epistaxis and second patient, her younger brother aged 1 year had history of gum bleeding and ecchymosis. GT is rare bleeding disorder. Still, in a case of unexplained bleeding in a child, one should suspect platelet function disorder. With proper supportive care Glanzmann’s thrombasthenia has a very good prognosis.
[Full Text Article]