EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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 ICV - 79.57

Abstract

STUDY OF CLINICAL MANIFESTATIONS AND OUTCOME OF RTPCR NEGATIVE COVID PNEUMONIA PATIENTS RECEIVING INJECTION REMDESIVIR.

Atharva Ajay Kulkarni*, Meenakshi Ashesh Bhattacharya, Sandesh Malu, Shrutika Kamble and Omkar Oak

ABSTRACT

Background: RTPCR is considered gold standard for diagnosis but because of False Negatives, HRCT scans are used as an aid for radiological diagnosis of COVID-19. Remdesivir is an antiviral pro-drug used to treat COVID-19 positive cases. But there are no treatment options for patients presenting as COVID pneumonia but testing negative by RTPCR. Methods add Period: We conducted a cross sectional observational study to find the outcome of RTPCR Negative Pneumonia patients receiving Remdesivir. Between June 2020 to January 2021, patients who tested negative after an RTPCR swab for SARS-CoV2 but were clinically or radiologically suspected to have COVID-19 were administered Remdesivir (200 mg on day one followed by 100 mg for the next four days) and their outcome, with demographic, clinical and radiologic characteristics of COVID-19 were assessed. Results: Out of 158 RTPCR Negative Pneumonia patients who received Remdesivir, 150 recovered (94.9%) and were discharged. 95 patients (60.12%) were Males. 61 patients belonged to age groups between 40-59 years (38.6%) and 65 patients were of the age ≥60 years (41.1%). 54 patients (34.1%) had some comorbidity, Hypertension being the most common, in 37 patients (23.4%). 91 patients (57.5%) belonged to Stage IIB. 39 patients (24.6%) had oxygen saturation <80% at admission of which 35 were discharged giving a recovery rate of 89.7%. Conclusion: It was observed that 94.9% RTPCR Negative COVID-19 pneumonia who received Inj. Remdesivir recovered and were discharged.

Keywords: COVID-19, RTPCR, Negative, Pneumonia, Remdesivir.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia