EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

CLINICAL EVALUATION OF TABLET GOKSHURA IN STAGE- I HYPERTENSION- AN OPEN LABEL RANDOMIZED CONTROL CLINICAL STUDY

Dr. Sunil H. Pal*, Dr. Eknath G. Kulkarni, Dr. Rajan B. Kulkarni and Dr. Sanjivani N. Rathod

ABSTRACT

Background: High blood pressure (BP) is ranked as the third most important risk factor for attributable burden of disease in South Asia (2010). The term Stage-1 Hypertension is reserved for about 95% of hypertensive, in which no immediately evident underlying renal or adrenal cause can be found for the raised Blood pressure. It can be only detected on routine medical check-up or when patient goes to hospital. Objectives: This open randomized clinically controlled study was conducted to clinically evaluate the efficacy of Tablet Gokshura in Stage- I Hypertension. Methods: 72 subjects of either sex of Stage-I Hypertension in the age group of 30-60 years were enrolled for the present study. Registered patients were randomly divided into two groups. In Group-A (Clinical study) patients were managed with Tablet Gokshura. Group-B (Controlled study) patients were managed with Tablet Tagara. The duration of trial was 30 days with follow up 0th day, 15th day and 30th day. Interpretation: After one month of therapy, statistically highly significant reduction in systolic B.P., diastolic B.P. mean arterial B.P. and pulse pressure was observed in both groups. Blood pressure was statistically significantly reduced in Group- A patients as compared to Group- B. Conclusion: On the basis of results obtained, it is clear that trial herbal Gokshura drug possess statistically significant anti-hypertensive activity with no observed side effects.

Keywords: Hypertension, Uccharaktachapa, Blood pressure, Gokshura, Tagara.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia