INSIGHTS INTO THE EMERGING WOUND HEALING POTENTIALS OF SOME IMPERATIVE INDIAN AND GLOBAL PLANTS

Dinesh Kumar*

ABSTRACT

The process by which skin heals itself is known as cutaneous wound healing. The four stages of cutaneous wound healing are universally accepted: hemostasis, inflammation, proliferation, and remodelling. Keratinocytes in humans quickly re-form a functioning epidermis (reepithelialization), sealing the lesion and restoring tissue homeostasis. Dysregulation in any step of the wound healing cascade slows healing and may lead to a variety of skin conditions, such as non-healing or chronic ulceration. Indigenous and traditional medicines make considerable use of natural goods and natural product derivatives, accounting for more than half of all medications utilized globally today. Recognizing the continuing importance of traditional medicine, we conducted a comprehensive review of the literature on the use of medicinal plants and plant-based products for cutaneous wounds. The active components, bioactivities, clinical applications, formulations, production techniques, and therapeutic value of 55 medicinal plant species are all described. Several species stand out as popular wound-healing remedies utilized by people of various cultures and ethnicities. Traditional traditions' popularity and evidence of continuous usage imply that there are still lessons to be gained from them. There are undescribed reagents, undiscovered combinations, and adjunct compounds hidden among the plethora of natural products and derivatives from natural products that might have a place in today's therapeutic inventory.

Keywords: Wound, Healing, Plants, Herbal, Extract, Phytochemicals.