CHEMICAL CONSTITUENTS FROM THE LEAVES OF EUCALYPTUS TERETICORNIS SM. AND VITIS VINIFERA L.

Mohammed Ali*, Shahnaz Sultana and Showkat Rasool Mir

ABSTRACT

Eucalyptus tereticornis Sm. (family Myrtaceae), is a native to eastern Australia and southern New Guinea, planted all over India after teak. A leaf decoction is drunk to cure asthma, burns, body pain, fever, influenza, diarrhoea, pulmonary problems and rheumatism. Vitis vinifera L. (family Vitaceae), is a long-stemmed, woody vine found in Mediterranean region, central Europe, and southwestern Asia. Its leaves are used to treat boils, diarrhoea and toothache. Our study was planned to isolate chemical constituents from methanolic extracts of the leaves of E. tereticornis and V. vinifera and to characterize their structures on the basis spectral data analysis. The methanolic extract of leaves of E. tereticornis afforded a known fatty acid ester identified as n-tricosanyl n-octadec-9-en-1-oate (n-tricosanyl oleate, 1), a new unsaturated aliphatic keto alcohol characterized as n- tricos-3β-ol-16-one-17(Z)-ene (2) and two new acyl coumarins and their structures have been established as 6-hexacosanoxycoumarin (6-cerotinoxycoumarin, 3) and n-(21′α-hydroxyoctacosanoxy) coumarin or (6-(21′α-hydroxymontanoxy) coumarin (4). The methanolic extract of the leaves of V. vinifera on subjection to silica gel column furnished steroidal esters characterized as stigmast-5-en-3 β-yl n-octadec-9, 12-dienoate (β- sitosterol linoleate, 5) and stigmast-5-en-3β-ol-3β-olyl n-docos-11-enoate (β-sitosterol 3β- cetoleate, 6).

Keywords: Eucalyptus tereticornis, Vitis vinifera, leaves, phytoconstituents, isolation, characterization.