EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

A REVIEW ON FORMULATION AND EVALUATION OF FAST DISSOLVING TABLET

Nishita Soni*, Dr. Dilip Agrawal, Ashok Kumar Sharma, Mohit Khandelwal and Dr. Rakesh Goyal

ABSTRACT

In this present scenario, the drug delivery system has become highly competitive and rapidly most evolving with ever increasing demand. Fast dissolving tablet (FDT) is such type of an innovative and unique drug delivery system which is intensly gaining much attention in the research field of rapid dissolving technology. Oral route is the most acceptable routes among all various routes for different patients of different age group because it is regarded as safest, convenient and economical route of administration. Therefore, recently many researcher and pharmaceutical companies developed fast dissolving tablet (FDT) by modifying the physio-chemical properties of drugs to their need with enhanced patient compliance and convenience. USFDA define FDTs to be the solid oral preparation that disintegrate rapidly in the buccal cavity with an in-vitro disintegration time of less than 30 seconds. FDTs improved patient compliance and also overcome the disadvantages of conventional dosage form especially dysphagia (difficulty in swallowing) in pediatric and geriatric patients. FDT formulations have the advantage over the both conventional tablet formulation as well as liquid dosage form. There are several methodologies that are conventional or patented based o spray drying, sublimation, melt granulation, direct compression, freeze drying/lyophilization, mass extrusion, etc. have been developed for manufacturing of FDTs. This review includes the requirements, advantages, limitations, various technologies developed for FDT, evaluation methods of fast dissolving tablets.

Keywords: Fast dissolving tablets (FDT), Super disintegrants, Dysphagia,, Bioavailability, Evaluation.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia