EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

EFFECT OF EARLY STARTING LOW-COST INDIGENOUS ENTERAL FEEDING FOR PANCREATODUODENECTOMY PATIENTS IN EARLY POST-OPERATIVE PERIOD

Dr. Md. Abdul Quiyum*, Dr. SM Ramiz Ahmed, Dr. Mohammad Zahirul Islam, Dr. ASM Firoz Mustafa, Dr. Omar Siddiqui, Dr. Muhiuddin Mahmud Galib and Dr. Md. Sidur Rahman Mollah

ABSTRACT

Background: Till date most of the time, nutrition after pancreatoduodenectomy (PD) is maintained by parenteral nutrition in the early postoperative period in our setting leading to higher mortality and morbidity. On the other hand, enteral feeding is practiced with commercially formulated costly preparation in rich countries which may not be affordable always in our situation. This study was conducted to see the effect of early enteral formulated feeding from locally available resources. Objective: To established a cost-effective enteral feeding protocol using indigenous food for treating PD patients in our setting. Methodology: Thirty patients who underwent PD in the Department of Hepatobiliary, Pancreatic & Liver Transplant Surgery, BSMMU, Dhaka from January 2020 to December 2020 were included in the study. They were categorized into two groups; Group A(n=15): enteral feeding made with indigenous food and started from POD 2 through nasojejunal tube with additional parenteral support and Group B(n=15): only parenteral nutrition without any enteral feeding continued up to six / seven POD. In all patients, serum albumin, total bilirubin, serum alkaline phosphatase, total count and CRP were measured on POD 1, 3, 7 & 14 for assessing nutritional, cholestatic, immunological and inflammatory status. Result: Serum albumin and lymphocyte count were significantly improved following 3rd POD onwards in Group A. The total bilirubin, alkaline phosphatase, total count and CRP were reduced faster in group A, but remained persistently elevated in Group B. In Group A, the morbidity and postoperative hospital stay were found significantly lesser than Group B. Group B had more nutrition related cost than group A. Conclusion: Early starting of enteral feeding prepared from indigenous food is an effective method of maintaining nutrition after PD. It improves the nutrition, immune condition, markedly reduces inflammation and cholestasis after PD and thus it reduces morbidity, post-operative hospital stays and nutrition related cost.

Keywords: Early and delayed Enteral feeding; indigenous food, early enteral nutrition, Pancreatoduodenectomy.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )