ADRENOCORTICAL CARCINOMA- A RARE CASE REPORT

Dr. Neha Mahajan*, Dr. Vaishali Nagose and Dr. Shirish Gondane

ABSTRACT

Adrenocortical carcinoma (ACC) is an uncommon and rare malignancy which arises from adrenal cortical cells. Half of the adrenocortical tumours are functional being associated with cushings syndrome or virilisation and rest of them present as a mass in abdomen or discovered incidentally during unrelated imaging procedures. We report a 46 year old female with complaints of heaviness and pain in abdomen. The patient had history of paroxysmal hypertension. The laboratory data showed no abnormality except for marginally raised Vannilyl mandelic acid levels. Ultrasonography Abdomen showed a solid echogenic mass measuring 8 x 5 x 5 cm in the right hypochondriac region in the upper pole in right kidney. The patient underwent nephrectomy with removal of adrenal mass and specimen sent for Histopathological examination. The diagnosis of adrenocortical carcinoma was made by morphology and was confirmed by Immunohistochemistry using specific markers.

Keywords: Adrenocortical carcinoma, paroxysmal hypertension, Cushing`s syndrome, Mass in abdomen.