EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

CLINICAL PROFILE OF SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) AND SPECTRUM OF ORGAN INVOLVEMENT: AN OBSERVATIONAL, CROSS-SECTIONAL, HOSPITAL BASED, SINGLE CENTER STUDY

Yasmeen Hynniewta*, Alakes Kumar Kole and Anirban Jana

ABSTRACT

Background: Systemic Lupus Erythematosus(SLE), is an autoimmune disorder affecting various organs and tissues. This observational, cross-sectional, hospital based, single center study undertaken in Nilratan Sircar Medical College and Hospital, Kolkata, was aimed to assess the clinical profile of SLE and spectrum of organ involvement. Materials and Methods: Between December 2015 to June 2017, 60 patients who were diagnosed cases of SLE according to Systemic Lupus Collaborating Clinics (SLIC) Criteria attending either outpatient or admitted at the medicine department of Nilratan Sircar Medical College and Hospital, Kolkata were included in the study. A detailed history, a thorough laboratory investigation and clinical examination in respect of different organ involvement was evaluated for each visit. Result: In this study, mean age and median of study population was 23.75 and 23 years. Only 3 patients were male whereas 57 were females, with female to male ratio of 5:95. Around 88.3% presented with constitutional symptoms, with fever. Musculoskeletal symptoms were present in 41.66%. Renal system involvement was seen in 23.3% patients of which, 31.7% patients had shortness of breath at presentation and 30% had associated edema. Conclusion: The study findings showed significantly higher number of cases in females of child bearing age with constitutional symptoms and musculoskeletal involvement, followed by mucocutaneous and renal involvement.

Keywords: Clinical profile, Musculoskeletal symptoms, Systemic Lupus Erythematosus.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )