EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

EFFECT OF XYLOPIA AETHIOPICA (NIGRO PEPPER) ON SOME BLOOD PARAMETERS IN MALE WISTAR RATS

Nsimah Monday Essien, Charles Cyprian Mfem, Sunday Okpa*, Justina Nwandimma Nwangwa, Ernest Atelhe Amama, Clement Lishilinimye Ushuple, Kendrick Okay Ococoh, Inah Onete Inah, Mfon Jeremiah Akpan

ABSTRACT

Background: This study investigated the effects of Xylopia aethiopica (Nigro pepper) on some blood parameters in male Wistar rats. Materials and Methods: Ten Wistar rats weighing 160 – 200g were divided into two groups (n=5). Control group received rat feed and water while the Xylopia aethiopica extract treated group received 10mg/kg b.w of the extract orally for 28 days. Results: Red cell distribution width, platelet count, plateletcrit, mean platelet volume, platelet distribution width and platelet large cell ratio were not significantly different between the two groups. Conclusion: The ethanolic extract of Xylopia aethiopica at a low dose of 10mg/kg b.w showed no significant effect on red cell distribution width and platelet indices. Further studies at higher doses of Xylopia aethiopica are encouraged to establish their clinical relevance in the management of hematological disorders.

Keywords: Xylopia aethiopica, blood, red blood cell, platelet.

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