EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

CAN CORD BLOOD BILIRUBIN BE USED AS PREDICTIVE MARKER FOR HYPERBILIRUBINEMIA IN NEWBORNS? A PROSPECTIVE STUDY

V. N. Nandanwar and N. S. Raghupathy*

ABSTRACT

Background: The most common causes of admission to hospital in the neonatal period is due to hyperbilirubinemia. Hyperbilirubinemia is a major contributor of morbidity in neonates. Prevention of serious complications is the main aim. Early discharge from the hospital which is widely seen now days might cause delay in recognition of hyperbilirubinemia. A remarkable biomarker identifier could be of real advantage and advancement. Methods: This study was undertaken to study weather cord blood bilirubin can be used as a predictor for hyperbilirubinemia. The study was taken up in the department of pediatrics of a tertiary teaching hospital. A total of 100 babies were taken for the study during the whole study period. The babies were examined and a detailed clinical examination was done at the time of birth and documented along with maternal history. The cord blood at the time of delivery and 48 hour serum blood was collected and sent to the lab for bilirubin level estimation. Results: The study consisted of 53 females and 47 males. Out of the 100 subjects 73 were caesarean and 27 were normal vaginal deliveries. With regard to term of gestation 72 babies were early term, 23 full-term and 5 late term. The mean cord bilirubin was 2.44mg/dl and the mean 48 hour serum bilirubin level was 13.12mg/dl. The incidence of hyperbilirubinemia in this study was 25%. The sensitivity was 35%, specificity was 75%, positive predictive value was 58.33%, negative predictive value 53.57%, false negative was 65% and false positive was 25%. Test for correlation was done between cord bilirubin and 48 hour serum bilirubin. There was moderate level (r > 0.3) of correlation which was highly significant (p < 0.001). Conclusion: This study concluded cord bilirubin can be used as a predictor for hyperbilirubinemia.

Keywords: Hyperbilirubinemia, cord blood and 48 hour serum blood.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )