EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

ROLE OF SERUM MAGNESIUM IN DIABETES MELLITUS: A CASE-CONTROL STUDY

Dr. Chandan Sharma*

ABSTRACT

Background: Diabetes-Mellitus (DM) is the most common endocrine disorder, encountered in clinical practice. At the same time, micronutrients are known as potential, preventive and therapeutic agents and among them, magnesium merits special attention. Magnesium is essential for insulin secretion, insulin receptor interaction or normal carbohydrate utilization. Therefore, the aim of this study was to analyse serum magnesium levels among diabetes mellitus patients. Method: A case-control study was performed on 80 diabetic patients, age >20 years, attending the outpatient Department of Medicine, Government Medical College, Jammu, for a period of 6 months. 40 age-matched healthy controls were also selected for the study. Results: Out of 80 Type 2 diabetics, 51.25% were between 40-60 years; 55% were males; 45% were females. Serum magnesium levels among normal healthy controls were 1.92 ± 0.23 mg/dl and 1.56 ± 0.46 mg/dl among cases, with 66.25% patients had mean range of 1.1-2.0 mg/dl. Mean HbA1c among patients was 7.67% ± 1.92%. Patients with longer duration of diabetes showed highest mean HbA1c values (8.04 %) and lowest mean serum magnesium values (1.36 mg/dl). 35 patients in the study group had one or more macro or micro vascular complications. Thus hypomagnesemia appeared to be an additional risk factor in the development and progression of DM. Conclusion: Since, the treatment of the diabetes requires a multidisciplinary approach whereby every potential complicating factor must be monitored and treated. It is advisable to include serum magnesium in the routine electrolyte panel for the better management of diabetes mellitus.

Keywords: .


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia