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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57



Dr. Harish S.*, Savita Pawar, Madhu Krishnamani and Gaurav Soni


Background: Tinospora cordifolia commonly named as “Guduchi” in Sanskrit belonging to family Menispermaceae is a genetically diverse, large, deciduous climbing shrub with greenish yellow typical flowers, found at higher altitude. In racemes or racemose panicles, the male flowers are clustered and female are solitary. The flowering season expands over summers and winters. A variety of active components derived from the plant like alkaloids, steroids, diterpenoid lactones, aliphatics, and glycosides have been isolated from the different parts of the plant body, including root, stem, and whole plant. Recently, the plant is of great interest to researchers across the globe because of its medicinal properties like antimicrobial, immune booster, anti-diabetic, anti-periodic, anti-spasmodic, anti-inflammatory, anti-arthritic, anti-oxidant, anti-allergic, anti-stress, anti-leprotic, anti-malarial, hepatoprotective, immunomodulatory and anti-neoplastic activities. (Soham Saha et al. 2012). The aqueous extract of T. cordifolia has been shown to protect against Escherichia coli and Staphylococcus aureus infections. T. cordifolia enhances the phagocytic and intracellular bactericidal activities of macrophages and neutrophils against E. coli-induced peritonitis. It has been shown to control the drug-resistance Mycobacterium tuberculosis infection by inducing Th1 immune responses. The stem of T. cordifolia has been used as a constituent in many Ayurvedic and Unani preparations for the treatment of general debility, dyspepsia, fever, and urinary diseases. The stem is used as diuretic, stimulates bile secretion, and cures jaundice. The extract of the stem is also useful in skin diseases and in combination with other drugs act as an antidote to snakebite. The dry bark of T. cordifolia has been shown to possess antipyretic, antiallergic, anti-inflammatory, and antileprotic properties. Moreover, T. cordifolia has been shown to be effective against diabetes mellitus. (Sultan Alsuhaibani et al. 2017). Tinospora cordifolia extract is a potent immune booster has been suggested in the treatment of various microbial infections. Hence this clinical trial is conducted to evaluate the safety and efficacy of Tinospora cordifolia extract in healthy adult volunteers. Objectives: The objective of this clinical study to evaluate comparative clinical Efficacy and Safety of BHC9633CP Tinospora cordifolia in Immune Support Adult Subjects. Conclusion: The final results of this study showed that Tinospora cordifolia is orally safe and effective in boosting immunity in healthy subjects. This clearly indicates that Tinospora cordifolia has definitive role in the management of infections as an immune support.

Keywords: NK-T cells, Investigational Product, Tinospora cordifolia, Efficacy and Safety.

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia