EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

FIBRODYSPLASIA OSSIFICANS PROGRESSIVA [FOP]: A REVIEW

Dondapati Lakshman Chaturvedhi*, K. Malleswari, D. Rama Brahma Reddy and B. Prasanna Kumar

ABSTRACT

Fibrodysplasia ossificans progressiva (FOP) is also known as Munchmeyer disease, Stoneman disease. It is a rare inherited connective tissue disease characterized by heterotopic ossification (atypical development of bone in the regions of the body where bone is not generally presen). A mutation in the gene ACVR1 is responsible for the disease. Specifically, ossification is typically first seen in the dorsal, axial, cranial and proximal regions of body. Diagnosis can be done by measuring clinically elevated levels of alkaline phosphatase. There is no approved treatment for FOP.

Keywords: Heterotopic ossification, ACVR1 gene, Alkaline phosphatase.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )