( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Md. Kutub Uddin Mollick*, Sukumar Saha, Utpal Kumar Chanda, Gazi Salahuddin and Mamun Al Mahtab


Objective: In this study our main goal is to evaluate the effectiveness of obeticholic acid and ursodeoxycholic in non alcoholic steatohepatitis management. Method: This cross sectional study was carried out at Tertairy Medical hospital January 2019 to January 2020. Where a total of 60 patients with a clinical and laboratory diagnosis of NASH, on a stable dose of UDCA for at least 6 months prior to screening, were randomly assigned (1:1:1) to one of three treatment groups for 85 days (3 months): OCA 10 mg, OCA 25 mg, OCA 50 mg or a matching placebo administered once daily. Results: During the study, out of 60 patients (40%) were 30 or below 30 years old, (26.6%) 31-40 years and (20%) 41-50 years and majority were male, 80%. C-reactive protein (CRP) showed significant reductions from baseline at the end of the study with OCA treatment. In OCA 25 mg group Improvement of fibrosis was 24% without worsening of NASH and 12% resolution cases of NASH with no worsening of fibrosis. Conclusion: Daily doses of OCA, ranging from 10 to 25 mg, significantly reduced levels of ALP, lipid profile, and alanine aminotransferase, compared to placebo, in patients with NASH who had inadequate responses to UDCA. Further study is needed for better outcome.

Keywords: obeticholic acid (0CA), ursodeoxycholic, nonalcoholic steatohepatitis (NASH).

[Full Text Article]




    December issue has been successfully launched on December 2023.

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 December 2023 Issue has been Published, Kindly check it on

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.


  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia