CLINICAL AND PATHOGENETIC ASPECTS FEATURES OF COVID-19 COURSE (DATA OF RETROSPECTIVE ANALYSIS)

Muminov Davron Kadirovich*

ABSTRACT

Aim of the study. Estimate of the clinical and pathogenetic characteristics of COVID-19 in the early rehabilitation period according to retrospective analysis. Material and research methods. A retrospective analysis of the case histories of 128 patients who underwent COVID-19 and persistent symptoms of the disease was carried out. The number and frequency of underlying diseases and clinical manifestations of various pathological syndromes were determined. The results of the analysis of case histories of patients showed that 44 patients suffered moderate severity of COVID-19, 45 patients - severe, 39 - extremely severe. 40 patients were diagnosed with a lesion of 25% of the lungs or less (CT-1), in 43 patients - more than 25 to 50% of the lung volume (CT-2), in 32 patients - more than 50 to 75% (CT-3) and in 13 patients - more than 75% (CT-4). On average, the number of background pathologies was 4.53 ± 2.20. The average number of background diseases was significantly higher in patients of the older age group (p <0.001). In patients with severe and extremely severe infections diabetes and obesity were more common (p <0.05 for both comparisons). Conclusion. According to the data of retrospective analysis, the average number of background diseases was significantly higher in patients of the older age group. Diabetes and obesity were more common in patients with severe and extremely severe COVID-19.

Keywords: COVID-19, clinical and pathogenetic variants of COVID-19, comorbid background.