A COMPARATIVE STUDY ON ASSESSMENT OF TREATMENT SATISFACTION AND QUALITY OF LIFE IN TYPE II DIABETES PATIENTS USING INSULIN AND ORAL HYPOGLYCEMIC AGENTS

Shailaja K.*, Abarna Lakshmi R., Nikhil Cherian Sam, Naveen Kumar P. and Mariya Martin

ABSTRACT

Background: Diabetes Mellitus is a chronic metabolic disease that requires continuous therapy and polypharmacy if uncontrolled DM is evident so that the effectiveness and adverse effects can affect the patient's quality of life and treatment satisfaction. Hence, both of them were the primary objectives of our study. Materials and Methods: An observational study was conducted in a tertiary care hospital for a period of 6 months. Patients with type II Diabetes mellitus on medication with insulin or oral hypoglycemic were included. The QOL instrument, WHOQOL-BREF questionnaire and the Diabetes Treatment Satisfaction Questionnaire [DTSQ] were administered to all patients at baseline, 3 months and 6 months of treatment. Statistical analysis was performed using SPSS 22 software. Student-t-test was used as a statistical test in the analysis. Results: In our study, 100 diabetic patients were enrolled, 50 in each group respectively. The glycemic profile was significantly better in the insulin group than oral hypoglycemic. When QoL is concerned in terms of domain, Insulin is higher in the psychological and social domain and OHA found better in the physical domain. There are no significant differences in the environmental domain. In treatment satisfaction, the Oral hypoglycemic group is significantly higher than the insulin group. Conclusion: Overall patients with Type 2 diabetes harm their quality of life with or without complications. It also shows that diabetes affects various domains such as physical functioning, emotional well-being, social functioning, economical status and general health in a patient's life, thereby affecting the QoL. Hence, it is recommended for patients to have adequate and strict glycemic control enabling them to maintain their quality of life, preventing disease progression and diabetic complications.

Keywords: Type II Diabetes, Insulin, Oral Hypoglycemics, WHOQOL BREEF, DTSQ.