A REVIEW: SILVER NANOPARTICLES IN WOUND HEALING

Sachin Vyavahare*, Nitin Padole and Jasmine Avari

ABSTRACT

Wound healing is achieved through a normal biological process in the human body with four precisely and highly programmed phases: Hemostasis, Inflammation, Proliferation, and Restoration. Successful wound healing must occur with the proper sequence of phases and time frame. Interference of many factors like bacterial infection, diabetes, obesity, smoking, and nutrition causing impaired wound healing. This article reviews the recent literature on wound healing ability of antibiotics and metallic nanoparticles. Influence of these factors on repair may lead to better understanding of the combination of antibiotics with different types of metallic nanoparticles to therapeutics that improve wound healing and resolve impaired wounds. Different types of antibiotics were used to release the pressure of infections which obliviously affect the wound healing process. Development of novel and potent bactericidal agents is of great clinical importance due to novel strains of the bacteria and other infectious microorganisms. Metallic Nanoparticles were investigated intensively due to their superior properties in physical, chemical, and biological aspects. It is essential to maximizing the proper knowledge of these properties and potential applications of Metallic Nanoparticles in several areas while minimizing their risks to humans and the environment. The aim of this paper to critically review metallic Nanoparticles from the perspectives of research trends in bacterial infection in Wound healing.

Keywords: Metallic nanoparticles, Wound healing, Antibacterial activity silver nanoparticles.